Friday, October 7, 2022

Week 1 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay pays 25-1

Broncos quarterback Russell Wilson will return to the Pacific Northwest to face his former team when the Denver Broncos battle the Seattle Seahawks in the first Monday Night Football game of the season. Wilson spent 10 seasons with the Seahawks, winning the Super Bowl in 2014, before being traded to the Broncos in March. Denver is favored by six points in the latest NFL odds from Caesars Sportsbook, while the over/under for total points scored is 42. The game is one of 16 on a loaded Week 1 NFL schedule. Other key NFL matchups include the reigning Super Bowl champion Rams hosting the Bills in the 2022 NFL Kickoff Game and the Cowboys and Buccaneers squaring off in a rematch of the Week 1 classic from last season. Before you make any Week 1 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception. The model enters the 2022 NFL season on an incredible 138-97 run on top-rated NFL picks that dates back to the 2017 season. Amazingly, it hasn’t missed a top-rated pick since Week 15 last season. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 1. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 1 NFL picks at SportsLine

Top Week 1 NFL picks

After simulating every game 10,000 times, the model is high on the Indianapolis Colts to cover as eight-point road favorites against the Houston Texans. The Colts enter the season with high hopes behind standout running back Jonathan Taylor. The 23-year-old back from Wisconsin was the league’s top runner last season, leading the NFL in rushing yards (1,811) and rushing touchdowns (18).

Taylor gashed the Texans last season. In two games against Houston, he ran for 288 yards and four touchdowns on 46 carries, averaging 6.3 yards per rush. In the first matchup between the teams, he averaged a season-best 10.4 yards a carry. Indianapolis beat Houston a combined 62-3 over the two games a season ago. See which other NFL parlay picks to make here.

How to make Week 1 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including an underdog that wins outright. You can only see the model’s NFL Week 1 best bets and parlay at SportsLine

What are the model’s top Week 1 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 1 NFL best bets from a model on a 138-97 run on its top-rated picks, and find out.

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